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Advancements in Autoantibody Testing for Thyroid Conditions

This educational activity will examine autoimmune related causality of thyroid dysfunction, and how testing for autoantibodies to the thyroid stimulating hormone receptor (TSHR) contribute to making an accurate diagnosis. Standard laboratory methods to determine functional activity of anti-TSHR will be discussed, along with anticipated bioassay advancements.

Target Audience
This activity is intended for medical professionals who have a clinical interest in thyroid disorders as seen in the following medical specialties: endocrinology, primary care (IM, FP, GP), obstetrics/gynecology, cardiology, pediatrics, laboratory medicine, nuclear medicine, ophthalmology, neurology, psychiatry, and sleep medicine.

Learning Objectives
After completing this activity, the participant should be better able to:

1. Explain the connection between thyroid autoantibodies and the thyroid stimulating hormone receptor.
2. Differentiate between critical thyroid laboratory tests such as binding assays, and bioassays that detect anti-TSHR antibodies.
3. Analyze current anti-TSHR testing versus developing anti-TSHR bioassays.

Faculty

Paul D. Olivo, MD, PhD
Immunologist and Molecular Biologist
Adjunct Assistant Professor Molecular
Microbiology and Microbial Pathogenesis 
Washington University Medical School
St. Louis, MO

 

 

 

 

 

Accreditation Statement
This activity is provided by Dane Garvin Ltd.

Physician Accreditation Statement – EACCME
EACCME accreditation is pending.

Physician Credit Designation – EACCME
EACCME accreditation is pending.

This activity was prepared by Paul D. Olivo, MD, PhD and recorded on June 20, 2024. Received ACCME approval on June 25, 2024 and EACCME approval on TBD.

Educational Grant
This educational activity is independently produced and is financially supported with an unrestricted educational grant by QuidelOrtho. 

References
Advancements in Autoantibody Testing for Thyroid Conditions

Last edited: 20-11-2024
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